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Tolbert could miss more than a month with a hairline fracture/bone bruise in his left leg, Joe Person of the Charlotte Observer reports.
Tolbert left Sunday's game in the fourth quarter with an apparent knee injury, ESPN's David Newton reports.
Tolbert (chest) was a limited practice participant Thursday, Steve Reed of the Associated Press reports.
Tolbert totaled negative five rushing yards on his four carries Sunday, but amassed 33 receiving yards on three catches in Carolina's Week 2 win over Detroit.
Tolbert carried seven times for 11 rushing yards and caught two passes (on four targets) for six receiving yards in Sunday's road win over the Buccaneers.