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Vargas pitched five scoreless frames, allowing just four hits and one walk while striking out six Twins in Wednesday's no-decision.
Vargas went four innings Thursday against the Indians, allowing two runs on two hits and a walk with four strikeouts.
Vargas allowed one run on two hits and one walk with striking out one over three innings in a 3-2 win over the Chicago White Sox on Saturday.
Vargas (elbow) was activated from the 60-day DL and will start Saturday against the White Sox, Josh Vernier of 610 Sports Radio AM reports.
Vargas (elbow) will start Saturday against the White Sox, Jeffrey Flanagan of MLB.com reports.
Vargas (elbow) pitched five innings Saturday for Triple-A Omaha, allowing four runs while striking out six batters and walking none.