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Qualls picked up his first hold of the season with a scoreless inning of relief Friday against the Rangers.
Qualls struck out one during a scoreless inning of relief Thursday in his 2015 season debut.
Qualls is slated to open the year in a setup role, with Luke Gregerson named the Astros' closer Tuesday, Brian McTaggart of MLB.com reports.
Astros manager A.J. Hinch isn't ready to announce his closer, Jose de Jesus Ortiz of the Houston Chronicle reports.
Qualls is expected to face competition from Luke Gregerson and Pat Neshek for the Astros' closer role in spring training.