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Santana did the heavy lifting offensively for the Indians Monday, knocking in three runs with on a double.
Updating an earlier report, Santana started Wednesday's game against the Yankees at first base.
Santana blasted his sixth home run of the season Sunday during Cleveland's defeat to Minnesota.
Santana went 6-for-9 with an RBI, a run scored, a double, and a stolen base in Sunday's double-header against the Royals on Sunday.
Santana will not play Wednesday at the White Sox due to the flu, the Cleveland Plain Dealer reports.
Santana supplied a solo home run and two runs scored en route to a 2-for-5 performance during Cleveland's win Sunday in Houston.
Santana (thumb) could return to the lineup Saturday, the team's official site reports. "He's progressing so well there's a chance he might play tomorrow," manager Terry Francona said Friday. "We'll see. It depends on how he gets through batting practice and everything, taking into consideration how cold it is and everything. But he's doing well."
Santana went 3-for-5 with a double, homer and pair of RBI in Thursday's 10-8 loss at Toronto.
The Indians plan on letting Santana catch as much as possible in the upcoming season, the team's official site reports.
Santana is not in the starting lineup Sunday against the Royals, the Indians' official Twitter page reports.
Santana went 3-for-6 with three runs scored, two home runs and five RBI against the Royals on Sunday.
Santana was removed from Wednesday's game due to a lack of hustle, the team's official site reports.
Santana, who homered for the second time in his last three games Saturday, is hitting .323 (10-for-31) over his last 10 games.
Santana went 3-for-4 with a double and two-run homer Sunday as Cleveland's comeback bid failed against Baltimore.
Santana went 2-for-4 Wednesday against the Rays with his sixth home run of the year, a three-run shot in the seventh inning.
Santana was dropped to the sixth spot in the batting order for the second consecutive game Tuesday.
Santana is not in the Indians' lineup Wednesday, according to the team's official Twitter page.
Santana (back) will return to the lineup for Monday's game against the Angels, according to the Indians' official Twitter page.
Santana (back) remains out of the starting lineup for Sunday's game against the Orioles, Jordan Bastian of MLB.com reports.
Santana (back) went through a pregame workout Saturday but is not guaranteed to return to the lineup Sunday, the team's official site reports.
Santana (back) is not in the starting lineup Thursday against the Orioles, MLB.com's Jordan Bastian reports.
Santana was removed from Friday's game in the ninth inning with tightness in his back, MLB.com's Jordan Bastian reports.
Santana is not in the lineup for Sunday's game against the Astros, according to the Indians' official Twitter page.
Santana (concussion) is in the lineup as the Indians' DH on Tuesday, Jordan Bastian of MLB.com reports.
Santana (concussion) will serve as the DH for Class-A Lake County on Monday, according to the Associated Press.
Santana (concussion) will likely rehab with Low-A Lake County on Monday before being activated Tuesday, Jordan Bastian of MLB.com reports.
Santana (concussion) has been cleared for cardio activities, the team's official site reports.
Santana (concussion) underwent some neurological tests Monday, the team's official site reports.
Santana (concussion) has been cleared to fly back to Cleveland with the team Sunday, Jordan Bastian of MLB.com reports.
The Indians placed Santana (head) on the 7-day concussion DL Saturday, Nick Camino of WTAM 1100 reports.
Santana was 1-for-3 with two walks, a run scored, and two RBI in Cleveland's loss to Boston Friday night.
Santana hit his fourth hommer and stole his first base of the season Wednesday against the White Sox.
Santana is not in the lineup for Sunday's game against the Athletics, Nick Camino of Newsradio WTAM 1100 reports.
Santana has agreed to a five-year, $21 million dollar contract with the Indians, Nick Camino of Newsradio WTAM 1100 reports.
Santana and the Indians are expected to announce an agreement on a multi-year contract Tuesday, the team's official site reports.
Santana will likely see fewer starts at first base with the addition of Casey Kotchman as the Indians will opt to use him as a DH when they want to keep Kotchman in the lineup and give Santana a day off behind the plate, Jordan Bastian of MLB.com reports.
Santana is back in the lineup for Game 1 of Saturday's doubleheader, MLB.com's Jordan Bastian reports.